Risdone 2mg Tabs 50’s treats schizophrenia and mania. Schizophrenia is a mental disorder that can result in hallucinations or delusions. Also, it adversely affects a person’s ability to think and behave. You can take the tablet with or without food, preferably at night. However, ensure you take it at the same time each day as this helps to maintain a consistent level of medicine in the body.