Educational Materials

General articles on diabetes management and prevention

#Insulin

Insulin is secreted in response to high blood glucose levels, Insulin stimulates the liver to: Convert and store glucose as glycogen, an inactive form of glucose. Inhibit the conversion of non-carbohydrates into glucose (gluconeogenesis). Insulin promotes facilitated diffusion of glucose through the membranes of cells that possess insulin receptors, e.g.…

#Sulphonylureas

Sulphonylureas are a class of oral (tablet) medications that controlblood sugar levels in patients withtype 2 diabetes by stimulating the production of insulin in the pancreas and increasing the effectiveness of insulin in the body. They are generally taken once or twice a day, with or shortly before a meal,…

#Prandial Glucose Regulators (#Glinides)

Prandial glucose regulators stimulate pancreatic beta cells to produce insulin Prandial glucose regulators, also known as glinides, are a family of oral medicines developed for the treatment of people with type 2 diabetes mellitus. They are taken up to three times a day prior to meals – up to 30…

#Incretin Mimetics (GLP-1 Agonists)

An injectable drug for patients unable to control diabetes with tablet medication Incretin mimetics are a relatively new group of injectable drugs for treatment of type 2 diabetes. The drugs, also commonly known as glucagon-like peptide 1 (GLP-1) receptor agonists or GLP-1 analogues, are normally prescribed for patients who have…

#DPP-4 Inhibitors #Gliptins

DPP-4 inhibitors are prescribed for type 2 diabetes patients who do not respond well to metformin and sulphonylureas Dipeptidyl peptidase-4 (DPP-4) inhibitors are a relatively new class of oral diabetes drugs. Also known as #gliptins, they are usually prescribed for people with type 2 diabetes who have not responded well…

#Biguanides

Biguanides prevent the production of glucose in the liver The term biguanide refers to a group of oral type 2 diabetes drugs that work by preventing the production of glucose in the liver, improving the body’s sensitivity towards insulin and reducing the amount of sugar absorbed by the intestines. The…

#Amylin Analogues

Amylin is a hormone produced by the pancreas and assists insulin in controlling post-meal glucose levels. Amylin analogues, or #Agonists, are injectable drugs used in the treatment of both type 1 diabetes andtype 2 diabetes. These compounds are administered before meals, and work similarly to the hormone amylin. Amylin has…

#Alpha Glucosidase Inhibitors

Alpha-glucosidase inhibitors slow down the digestion of carbohydrates Alpha-glucosidase inhibitors (AGIs), sometimes referred to as starch blockers, are anti-diabetic medicines that help to reduce post meal blood glucose levels. Unlike most other types of diabetes drugs, they don’t have a direct effect on insulin secretion or sensitivity. Instead they work…
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